Estimated proportion with 95% CI of complications/events for endoscopy and microscopy
| Complication/events | No of studies for endoscopy | Proportion (95% CI) for endoscopy | No of studies for microscopy | Proportion (95% CI) for microscopy |
|---|---|---|---|---|
| Death | 19 | 0.49% (0.23% to 0.84%)† | 18 | 0.23% (0.10% to 0.42%)† |
| Cerebrospinal fluid leak | 24 | 7.00% (4.84% to 9.52%) | 19 | 6.34% (3.86% to 9.37%) |
| Meningitis | 13 | 1.11% (0.64% to 1.71%)† | 14 | 2.08% (0.83% to 3.86%) |
| Vascular complications* | 17 | 1.58% (1.07% to 2.19%)† | 12 | 0.50% (0.28% to 0.78%)† |
| Visual loss | 13 | 0.72% (0.37% to 1.19%)† | 14 | 0.60% (0.23% to 1.14%) |
| Diabetes insipidus temporary | 18 | 9.10% (6.57% to 11.99%) | 14 | 10.23% (6.50% to 14.69%) |
| Diabetes insipidus permanent | 21 | 2.31% (1.41% to 3.41%) | 15 | 4.25% (1.96% to 7.36%) |
| Hypopituitarism | 17 | 8.51% (5.16% to 12.59%) | 12 | 11.64% (5.14% to 20.32%) |
| Complete resection | 22 | 68.77% (64.37% to 73.00%) | 18 | 64.44% (57.62% to 70.98%) |
| Nerve injury | 8 | 0.28% (0.05% to 0.71%)† | 7 | 0.53% (0.08% to 1.34%) |
*Vascular complication rate is higher using the endoscope than using the microscope (p<0.0001).
†A fixed-effects pooled estimate is used for the proportions. Otherwise, a random-effects pooled estimate is used.