Tardive dystonia
| Reference | Age at surgery (years), mean (range) | Disease duration (years), mean (range) | Stimulationparameters R/L | Pre-op severityscore, mean (range) | Post-op severityscore, mean (range) | % Improvementat last F/U | F/U |
|---|---|---|---|---|---|---|---|
| Chang et al106 n=5 | 57.8 (28–59) | 10.6 (6–20) | 3.14±0.5 V/2.9±0.45 V 204±13.4/198±16.4 µs 130±56 Hz | BFM (mov) 47.9 BFM (dis) 11.8 | BFM (mov) 14.5 BFM (dis) 6.2 | 70.9±12% 47.9±18% | 34 months (15–76) median (range) |
| Capelle et al107 n=4 | 45 | 4 | gr parameters 4.5 V (3.0–6.5) 90–210 µs 130–160 Hz | BFM (mov) 65 BFM (dis) 8 | BFM (mov) 5.5 BFM (dis) 1 | 91% 88% | 27 months |
| 76 | 11 | 55 6 | 16 3 | 70% 50% | 30 months | ||
| 65 | 7 | 18 1 | 2 0 | 88% 100% | 16 months | ||
| 48 | 5 | 33 8 | 4.5 4 | 87% 50% | 36 months | ||
| Gruber et al102 n=9 | 63.2 (38–76) | 5.3 (2–11) | 3.0±1.0 V/2.8±0.6 V 83.3±13.2 µs 154±25.1 Hz | – – – | – – – | BFM (mov) 83±12.2% BFM (dis) 67.7±28% AIMS 78.7±19.9% | 41 months (18–80) mean (range) |
| Katsakiori et al108 n=1 | 40 | 3 | N/A | BFM (mov) 35 BFM (dis) 19 | BFM (mov) 2 BFM (dis) 3 | 94% 84% | 12 months |
| Kefalopoulou et al109 n=1 | 42 | 3 | 2.5–3.6 V 250–400 µs 185 Hz | BFM (mov) 52 AIMS 30 | BFM (mov) 4.5 AIMS 7 | 91% 77% | 6 months |
| Magarinos-Ascone et al110 n=1 | 59 | 4 | N/A | BFM (mov) 46 BFM (dis) 16 | BFM (mov) 24 BFM (dis) 9 | 48% 44% | 12 months |
| Sako et al105 n=6 | 44.5 (31–64) | 3.1 (0.5–6) | 2.2±0.9 V 450 µs 119±28 Hz | – – | BFM (mov) 86±14% BFM (dis) 80±12% | 21 months | |
| Pretto et al111 n=1 | 72 | N/A | 4.0 V 90 µs 185 Hz | BFM (mov) 1 | 90% | 3 months | |
| Cohen et al104 n=2 | 44 | 4 | 4 V 90 µs 130 Hz | BFM (mov) 3 BFM (dis) 0 | 86% 100% | 13 months | |
| 50 | 4 | 4 V 120 µs 130 Hz | 31.5 19 | 11.5 9 | 64% 53% | 7 months | |
| Damier et al112 n=10 | 45.1 (26–69) | 4.5 (1–10) | 3.5±0.2 v 150 µs 130 Hz | – – | – – | ESRS 61% (44–75) AIMS 56% (33–69) | 6 months |
| Starr et al27 n=4 | 36 | 7 | N/A | BFM (mov) 11 | BFM (mov) 0 | 100% | 26 months |
| 47 | 4 | N/A | 38 | 7.5 | 80% | 27 months | |
| 59 | 20 | N/A | 57 | 53.5 | 6% | 17 months | |
| 36 | 10 | N/A | 80 | 37.5 | 53% | 9 months | |
| Zhang et al113 n=1 | 28 | 3 | STN bilat 1.5 V/3.0 V 90 µs 185 Hz | BFM (mov) 98.5 UDRS 94 | BFM (mov) 8 UDRS 7.5 | 92% 92% | 3 months |
| Franzini et al100 n=2 | 33 | 5 | 1 V 90 µs 130 Hz | BFM (mov) 36 | BFM (mov) 5 | 86% | 12 months |
| 30 | 3 | 1 V 90 µs 130 Hz | 70 | 8 | 89% | 13 months | |
| Trottenberg et al103 n=5 | 56.2 (30–70) | N/A | 2.7±0.8 V 111±57 µs 144±22 Hz | BFM (mov) 32 BFM (dis) 8 | – – | 87% 96% | 6 months |
| Krause et al26 n=2 | 53.7 | 5.7 | N/A | BFM (mov) 62 | BFM (mov) 63.5 | −2% | 30 months |
| 47.6 | 22.6 | N/A | 76 | 77 | −1% | 42 months | |
| Eltahawy et al20 n=1 | 53 | 4 | 2.6 V 210 µs 40 Hz | BFM (mov) 52 | BFM (mov) 21 | 60% | 18 months |
| Yianni et al18 n=1 | 40 | 5 | N/A | AIMS 24 | AIMS 14 | 42% | 12 months |
AIMS, Abnormal Involuntary Movement Scale; action, action subscore; BFM, Burke–Fahn–Marsden Dystonia Rating Scale; bilat, bilateral; dis, disability subscore; ESRS, Extrapyramidal Symptom Rating Scale; F/U, follow-up; funct, functional subscore; GPi, internal globus pallidum; L, left; mov, movement subscore; n, number of individual in each study; N/A, not available; NST, ; pre-op, preoperative state; post-op, postoperative state; R, right; rest, rest subscore; tot, total subscore; UMRS, Unified Myoclonus Rating Scale; STN, subthalamic nucleus.