The impact of health on the activities of daily living in subjects with Parkinson's disease (PD-non-RBD) and Parkinson's disease and probable REM sleep behaviour disorder (PD-RBD)
| PD-non-RBD (n=251) | PD-RBD (n=224) | Adjusted difference in means* (PD-RBD—PD-non-RBD) (95% CI) | p Value* | ||
|---|---|---|---|---|---|
| EQ-5D | Continuous measures | ||||
| Patient-reported health score | 71.9±16.9 | 66.4±19.6 | −5.05 (−8.32 to −1.78) | 0.003 | |
| Binary measures | Adjusted OR* (95% CI) | ||||
| Problems with mobility, % | 44.2 | 54.3 | 1.46 (1.01 to 2.12) | 0.04 | |
| Problems with self-care, % | 18.4 | 27.8 | 1.72 (1.11 to 2.64) | 0.02 | |
| Problems with activities, % | 39.8 | 53.2 | 1.68 (1.16 to 2.44) | 0.006 | |
| Problems with pain, % | 55.8 | 64.9 | 1.52 (1.03 to 2.25) | 0.03 | |
| Problems with anxiety and depression, % | 33.5 | 51.6 | 2.16 (1.49 to 3.13) | <0.001 | |
*Adjusted for age, sex, disease duration and smoking history.