Table 2

FTM tremor rating scale, clinical scores in the on and off states

FTM scale, itemMaximal possible scoreNon-blinded
DBS ‘off’
Non-blinded
DBS ‘on’
Blinded
DBS ‘off’
Blinded
DBS ‘on’
p Value*p Value†
Sum ETRS (1–14)11658.6234.0856.0735.23<0.001<0.001
Tremor scores (1–9)8029.6212.8528.214.850.0010.002
 Voice tremor41.380.772.082.150.0010.673
 Head tremor‡81.230.381.380.690.0110.013
Tremor upper extremity§
 Ipsilateral127.55.336.335.50.0770.197
 Contralateral128.73.558.74.0<0.001<0.001
RUE (item 5)
 Rest42.150.082.150.23<0.0010.001
 Postural42.770.922.851.15<0.0010.002
 Action42.771.542.771.620.0010.002
Handwriting (item 10)42.691.462.231.310.0020.002
Hand function (items 11–14)
 Ipsilateral1611.6711.010.679.830.1020.102
 Contralateral1613.559.5513.759.45<0.0010.001
  • *Comparison between non-blinded DBS on/off.

  • †Comparison between blinded on/off DBS.

  • ‡Includes rest and postural tremor.

  • §Includes, rest postural and action tremor. Contralateral hemibodies n=20, ipsilateral hemibodies n=6.

  • DBS, deep brain stimulation; ETRS, Essential Tremor Rating Scale; FTM, Fahn–Tolosa–Marin; RUE, right upper extremity.