General demographic characteristics of the cohort by vital status at December 2012
| Deceased (n=80) | Alive (n=843) | p Value | |
|---|---|---|---|
| Age (mean (SD)) | 56 (±12) | 51 (±10) | =0.001 |
| Sex (female %) | 34 (42%) | 610 (72%) | <0.001 |
| Last recorded EDSS (median (range)) | 7.5 (6.5–8.0) | 5.5 (3.0–6.5) | <0.001 |
| MSSS (mean (SD)) | 7.9 (±2.23) | 5.34 (±2.59) | <0.001 |
| Age at the onset (mean (SD)) | 35 (±10.67) | 32 (±9.74) | =0.02 |
| Disease duration (median (range)) | 18 (10–26) | 15 (9–23) | =0.06 |
| Type of MS | <0.001 | ||
| Relapsing-remitting | 9 (11%) | 445 (52%) | |
| Primary-progressive | 16 (20%) | 87 (10%) | |
| Secondary-progressive | 55 (69%) | 311 (37%) | |
| DMT ≥1 year | 13 (16%) | 384 (45%) | <0.001 |
DMT, disease-modifying treatment; EDSS, expanded disability status scale; MSSS, multiple sclerosis severity score.