Patient characteristics
| Delayed cerebral ischaemia | Poor outcome | |||
|---|---|---|---|---|
| No (n=155) | Yes (n=97) | No (n=94) | Yes (n=108) | |
| Demographics | ||||
| Age, years | 57.1±14.1 | 56.0±13.5 | 53.1±12.0 | 60.5±15.6 |
| Gender, male | 47 (30.3) | 26 (26.8) | 34 (36.2) | 28 (25.9) |
| Ethnicity, white | 68 (43.9) | 41 (42.3) | 45 (47.9) | 51 (47.2) |
| Risk factors and comorbidities | ||||
| Hypertension | 85 (54.8) | 46 (47.4) | 46 (48.9) | 56 (51.9) |
| Smoking | 61 (39.4) | 34 (35.1) | 40 (42.6) | 29 (26.9) |
| Alcohol | 14 (9.0) | 11 (11.3) | 12 (12.8) | 6 (5.6) |
| Stroke | 12 (7.7) | 4 (4.1) | 3 (3.2) | 11 (10.2) |
| Cardiac disease | 16 (10.3) | 8 (8.2) | 4 (4.3) | 17 (15.7) |
| Pulmonary disease | 10 (6.5) | 4 (4.1) | 6 (6.4) | 7 (6.5) |
| Initial assessment | ||||
| GCS | 8 (6–10) | 8 (6–10) | 9 (7–14) | 7 (5–10) |
| Hunt–Hess grade | ||||
| 1 | 5 (3.2) | 4 (4.1) | 8 (8.5) | 1 (0.9) |
| 2 | 7 (4.5) | 3 (3.1) | 7 (7.4) | 1 (0.9) |
| 3 | 41 (26.5) | 23 (23.7) | 24 (25.5) | 28 (25.9) |
| 4 | 64 (41.3) | 44 (45.4) | 41 (43.6) | 41 (38.0) |
| 5 | 38 (24.5) | 23 (23.7) | 14 (14.9) | 37 (34.3) |
| Modified Fisher scale | ||||
| 1 | 19 (12.3) | 6 (6.2) | 7 (7.4) | 12 (11.1) |
| 2 | 21 (13.5) | 7 (7.2) | 12 (12.8) | 12 (11.1) |
| 3 | 63 (40.6) | 40 (41.2) | 38 (40.4) | 42 (38.9) |
| 4 | 52 (33.5) | 44 (45.4) | 37 (39.4) | 42 (38.9) |
| Hijdra scale | 18.3±7.4 | 19.8±8.4 | 18.8±7.7 | 18.6±7.8 |
| Global cerebral oedema, initial CT | 41 (26.5) | 32 (33.0) | 26 (27.7) | 28 (25.9) |
| Aneurysm size, mm | 8.7±6.7 | 8.0±4.5 | 7.5±3.9 | 9.9±7.5 |
| APACHE II score | 17.5±7.0 | 18.0±6.2 | 16.2±6.5 | 19.3±6.7 |
| Follow-up assessment | ||||
| Rebleeding | 20 (12.9) | 21 (21.6) | 8 (8.5) | 24 (22.2) |
| Global cerebral oedema, follow-up CT | 111 (71.6) | 85 (87.6) | 60 (63.8) | 92 (85.2) |
| Hydrocephalus | 110 (71.0) | 74 (76.3) | 64 (68.1) | 85 (78.7) |
| Intracranial pressure crisis | 95 (61.3) | 75 (77.3) | 61 (64.9) | 74 (68.5) |
| Meningitis | 25 (16.1) | 20 (20.6) | 14 (14.9) | 25 (23.1) |
| Pneumonia and/or pulmonary oedema | 96 (61.9) | 73 (75.3) | 55 (58.5) | 84 (77.8) |
| Sepsis | 28 (18.1) | 28 (28.9) | 12 (12.8) | 28 (25.9) |
| Exposure to hyperoxia | 28 (18.1) | 36 (37.1) | 18 (19.1) | 32 (29.6) |
| Exposure to hypocarbia | 25 (16.1) | 23 (23.7) | 15 (16.0) | 21 (19.4) |
Values are number (column %), mean±SD, or median (IQR), as appropriate.
APACHE II, Acute Physiology and Chronic Health Evaluation II; GCS, Glasgow coma scale.