Demographic, clinical and radiological characteristics of the patients studied in each centre, at study entry
| Characteristics | Amsterdam | Barcelona | Bordeaux | London | Milan |
| Patients (n) | 20 | 22 | 4 | 22 | 12 |
| Gender (F/M) | 10/10 | 9/13 | 3/1 | 11/11 | 2/10 |
| Age (years) (mean (range)) | 53.5 (76–34) | 45.7 (31–64) | 48.7 (43–59) | 52.7 (29–74) | 45.1 (32–50) |
| Disease duration (years) (mean (range)) | 11.7 (2–32) | 8.8 (3–24) | 9.0 (2–11) | 10.3 (1–24) | 6.8 (2–17) |
| EDSS score (median (range)) | 6.0 (2–8) | 5.5 (2–7.5) | 5.0 (4–6) | 6.0 (2.5–8.5) | 4.0 (2–8.5) |
| T2 lesion load (ml)(mean (SD)) | 8.4 (11.0) | 15.8 (16.0) | 12.6 (17.7) | 15.3 (17.5) | 7.7 (5.7) |
| T1 lesion load (ml)(mean (SD)) | 3.4 (4.9) | 5.6 (7.2) | 6.0 (7.7) | 4.7 (7.7) | 3.8 (6.6) |
| Spinal cord area (mm2) (mean (SD)) | 72.3 (10.1) | 77.9 (8.2) | – | 70.3 (9.4) | 77.4 (8.1) |
EDSS, Expanded Disability Status Scale.