Time of occurrence of symptoms/signs present both in codon 129 MM and codon 129 MV patients
| Symptom/sign | N patients (%) | Mean±SD (weeks) | Median (weeks) | |||
|---|---|---|---|---|---|---|
| Genotype | MM (n=17) | MV (n=6) | MM (n=17) | MV (n=6) | MM (n=17) | MV (n=6) |
| Vegetative | 13 (77) | 6 (100) | 4±0 | 18.5±3 | 0 | 23 |
| Sleeping disturbances | 17 (100) | 5 (83) | 3±0 | 15±0 | 0 | 0 |
| Bulbar | 5 (29) | 5 (83) | 19±0.5 | 23±16 | 11 | 20 |
| Visual | 11 (65) | 5 (83) | 13±1 | 6±2 | 12 | 2 |
| Cognitive/mnestic | 14 (82) | 6 (100) | 13±0 | 16±0 | 12 | 20 |
| Hallucinations | 12 (71) | 2 (33) | 16±0 | 57.5±19 | 14 | 57.5 |
| Spatial disorientation | 13 (77) | 2 (33) | 20±2 | 38.5±1 | 16 | 38.5 |
| Ataxia | 13 (77) | 6 (100) | 21±4 | 9±2 | 20 | 4 |
| Dysarthria | 10 (59) | 4 (67) | 21±0 | 27±0.5 | 20 | 28.5 |
| Myoclonus | 13 (77) | 3 (50) | 16±1 | 32±3.5 | 21 | 32 |
| Pyramidal | 8 (47) | 2 (33) | 29.5±5 | 28±5 | 26 | 28 |