Values of PBVC/y according to age, MS type and use of DMTs during follow-up
| Subject characteristics | Mean PBVC/y (SD), % | p Value |
|---|---|---|
| Age at baseline (HC) | ||
| ≤35 (n=16) | −0.20 (0.13) | 0.02 |
| >35 (n=19) | −0.32 (0.14) | |
| Age at baseline (patients with MS ) | ||
| ≤35 (n=92) | −0.52 (0.28) | 0.8 |
| >35 (n=114) | −0.51 (0.28) | |
| MS type | ||
| Relapsing (n=180) | −0.52 (0.29) | 0.2 |
| Progressive (n=26) | −0.45 (0.18) | |
| DMTs during follow-up | ||
| No (n=31) | −0.43 (0.28) | 0.1 |
| Yes (n=175) | −0.53 (0.27) | |
DMTs, disease-modifying treatments; HC, healthy controls; MS, multiple sclerosis; PBVC/y, annualised percent brain volume change.