Baseline demographic, clinical and neuroradiological factors in 548 patients with primary intracerebral haemorrhage in the ENOS trial
| Variable | Data |
|---|---|
| Demographics | |
| Age (years) | 67.9 (12.1) |
| Sex, male (%) | 360 (65.7) |
| Country, UK (%) | |
| Asia | 117 (21.4) |
| Europe | 67 (21.4) |
| Other (Africa, Australasia and North America) | 42 (7.7) |
| UK | 322 (58.8) |
| Clinical findings | |
| Premorbid modified Rankin Scale=0 (%) | 418 (76.3) |
| Previous stroke (%) | 69 (12.6) |
| Prior antihypertensive medication use (%) | 227 (41.4) |
| Prior history of high BP (%) | 341 (62.2) |
| Diabetes mellitus (%) | 67 (12.2) |
| Ischaemic heart disease (%) | 56 (10.2) |
| Atrial fibrillation (%) | 30 (6.5) |
| Total anterior circulation syndrome (%) | 195 (35.6) |
| SSS (/58) | 30.1 (12.3) |
| National Institutes of Health Stroke Scale (/42) | 12.8 (5.3) |
| Systolic BP (mm Hg) | 171.6 (19.3) |
| Diastolic BP (mm Hg) | 92.2 (13.3) |
| Heart rate (bpm) | 77.7 (14.5) |
| Time, stroke to neuroimaging (h) | 4.5 [11.6] |
| Adjudicated CT scan findings | |
| Location of haemorrhage (%) | |
| MCA | 346 (63.1) |
| ACA | 22 (4.0) |
| PCA | 5 (0.9) |
| MCA+ACA | 2 (0.4) |
| Borderzone | 14 (2.6) |
| Lacunar (ie, small subcortical) stroke | 142 (25.9) |
| Brainstem and/or cerebellum | 16 (2.9) |
| Leukoariosis | 362 (66.1) |
| Lesion mass effect (minimal to extreme swelling) | 470 (85.9) |
| Previous stroke lesion | 270 (49.3) |
| IVH | 141 (25.7) |
| Intracerebral haematoma size category (%) | |
| <3 cm | 220 (40.6) |
| 3 to <5 cm | 224 (41.3) |
| 5 to 8 cm | 87 (16.1) |
| >8 cm | 11 (2.0) |
| Measured CT scan findings | |
| Volume, ABC/2 (cm3) | 12.77 (16.32) |
| Longest diameter (cm) | 3.38 (1.4) |
| With IVH, n=141 | |
| Graeb score (/12)16 | 3.52 (2.4) |
| Modified Graeb score (/32)17 | 5.19 (4.7) |
| Without IVH, n=407 | |
| Shape (/5)15 | 3.00 (1.4) |
| Shape index22 | 1.22 (1.1) |
| Density (/5)15 | 2.54 (1.3) |
| Density index23 | 0.19 (0.1) |
Data are number (%), median (semiquartile range), or mean (SD).
NIHSS calculated from SSS scores range from 0 (comatose with quadriplegia) to 58 (normal neurological status).
ACA, anterior cerebral artery territory; BP, blood pressure; ENOS, Efficacy of Nitric Oxide in Stroke; IVH, intraventricular haemorrhage; MCA, middle cerebral artery territory; NIHSS, the National Institutes of Health Stroke Scale; PCA, posterior cerebral artery territory; SAS, semiautomatic segmentation; SSS, Scandinavian Stroke Scale.