Effects of covariates on time from diagnosis to respiratory involvement: multivariate analysis
| Variable | Onset-site group | Coefficient | 95% CI (main analysis) | 95% CI (80% sample) | p Value (main analysis) |
|---|---|---|---|---|---|
| Baseline mean | Bulbar | 4.43 | 2.7 to 7.3 | 3.5 to 5.9 | |
| Log scale | Limb | 4.86 | 3.3 to 7.1 | 3.9 to 6.2 | |
| Baseline SD | Bulbar | 0.97 | 0.85 to 1.11 | 0.89 to 1.03 | |
| Log scale | Limb | 1.32 | 1.19 to 1.48 | 1.24 to 1.37 | |
| Age at symptom onset (years) | Bulbar | −0.0185 | −0.025 to −0.012 | −0.022 to −0.016 | 2×10−9 |
| Limb | −0.0223 | −0.028 to −0.017 | −0.026 to −0.019 | 9×10−16 | |
| Diagnostic delay (months) | Bulbar | 0.130 | 0.039 to 0.220 | 0.079 to 0.174 | 0.005 |
| Limb | 0.140 | 0.063 to 0.215 | 0.094 to 0.180 | 0.0003 | |
| Riluzole use | Bulbar | 0.228 | 0.077 to 0.380 | 0.16 to 0.29 | 0.003 |
| Limb | 0.205 | 0.057 to 0.353 | 0.12 to 0.29 | 0.006 |