Double-blind study doxycycline | Double-blind study control (placebo) | |||||||
---|---|---|---|---|---|---|---|---|
Secondary outcome measures | BL | 1TV | 2TV | 8W | BL | 1TV | 2TV | 8W |
Probability of deficits in sphincter function (patients at risk) | 43% (7) | 62% (3) | 81% (1) | 81% (1) | 40% (5) | 80% (3) | 80% (1) | 80% (1) |
Probability of needing help in feeding/nutrition (patients at risk) | 71% (7) | 86% (2) | 86% (1) | 100% (1) | 80% (5) | 80% (1) | 80% (1) | 100% (1) |
Probability of akinetic mutism (patients at risk) | 0% (7) | 0% (6) | 33% (6) | 33% (2) | 0% (5) | 20% (5) | 20% (2) | – (0) |
1TV, First telephone interview 2 weeks after baseline; 2TV, second telephone interview 4 weeks after baseline; 8W, 8 weeks; BL, baseline.