Baseline demographic Parkinson's disease motor, cognitive and other measures in each group
| HC | PD-Psy0 | PD-Psy1+ | PD-Psy2+ | |
|---|---|---|---|---|
| n=144 | n=286 | n=115 | n=21 | |
| Demographic | ||||
| Age (years) | 59.79±11.5 | 61.97±9.9 | 60.77±9.6 | 64.43±7.5 |
| Gender | M=60% | M=67% | M=62% | M=71% |
| PD | ||||
| Duration (months) | 6.51±6.3 | 6.92±7.2 | 8.52±7.2 | |
| UPDRS part 111 | 1.33±2.4 | 21.1±8.8 | 20.08±9.0 | 21.90±7.6 |
| Tremor onset % | 79 | 75 | 76 | |
| Bradykinesia onset % | 81 | 87 | 85 | |
| Rigidity onset % | 77 | 74 | 76 | |
| Postural onset % | 7 | 6 | 9 | |
| Other onset % | 17 | 16 | 14 | |
| Left/symmetric onset | 43 | 47 | 47 | |
| Non-cognitive | ||||
| RBD | 2.66±2.0 | 2.91±2.5 | 3.97±2.8 | 5.38±3.4 |
| Olfaction | 33.95±4.7 | 22.78±8.2 | 21.02±8.0 | 17.9±7.3 |
| GDS | 1.31±2.2 | 2.18±2.4 | 2.72±2.5 | 4.24±3.3 |
| Cognitive | ||||
| MoCA | 28.2±1.0 | 27.1±2.3 | 27.16±2.3 | 26.29±3.0 |
| PD-MCI | 24% | 18% | 28% | |
| Fluency | 52.1±11.2 | 48.58±11.6 | 48.11±11.4 | 43.86±11.2* |
| Hopkins delay | 9.27±2.3 | 8.26±2.5 | 8.65±2.4 | 7.71±3.0 |
| Benton line | 13.11±2.0 | 12.93±2.0 | 12.60±2.2 | 11.76±2.5 |
| Letter number | 10.97±2.5 | 10.52±2.6 | 10.68±2.6 | 9.8±2.9 |
Shaded cells indicate group comparisons between PD-Psy0 and PD-Psy1+ or PD-Psy2+ significant at p<0.05 (t-tests for independent samples).
*p=0.07 trend significance.