Multivariate linear regression models for motor symptom severity in patients with PD as assessed by UPDRS part III scores
| Independent variables | Coefficient | SE | r | t | p Value |
| Constant | −0.530 | ||||
| Disease duration (years) | 0.361 | 0.177 | 0.303 | 2.038 | 0.048* |
| Age (years) | 0.173 | 0.107 | 0.246 | 1.625 | 0.112 |
| Gender (male) | 4.021 | 2.688 | 0.228 | 1.496 | 0.142 |
| Plasma α-synuclein level | 0.213 | 0.176 | 0.186 | 1.213 | 0.232 |
In this model, the motor score of UPDRS (part III) in the on state was set as the dependent variable, with age, gender, disease duration and plasma level of α-synuclein set as independent variables. r: correlation coefficient based on the model of multiple linear regression; t: t value for the coefficient of each parameter in the model; p: for r or t; R2-adjusted=0.1998, p=0.01 for the model. *: statistically significant, p<0.05; **: p<0.01.
PD, Parkinson’s disease; UPDRS, Unified Parkinson’s Disease Rating Scale.