Table 3

Prevalence of posterior pituitary dysfunction following TBI

Study n GCS Time from injury % of posterior hypopituitarism (cranial diabetes insipidus)
<1  month
Hannon et al 50 100<14Median 6 days51
Hadjizacharia et al 21 4363–15Mean 1.2 days15
Agha et al 57 50<141–3 days26
Agha et al 55 102<14Acute21.6
Agha et al 56 50<14Median 12 days26
Boughey et al 54 ––Mean 1.5 days2.9
>1  month
Bavisetty et al 58 70Median 76–9 months1.4
Agha et al 57 50<146 months8
12 months6
Agha et al 55 102<14Median 17 months6.9
Aimaretti et al 24 1003–153 months4

  • GCS, Glasgow Coma Scale; TBI, traumatic brain injury.