Table 1

Demographic data and sleep-related symptoms in the patients with PD and controls

PDControlsp Value
n (male/female)436 (197/239)401 (187/214)0.67
Age (years)69.3±7.869.2±8.60.38
Education (years)12.5±2.812.2±2.80.10
Caffeine intake, n (%)381 (87.4)342 (85.3)0.38
Caffeine (cup/day)2.5±2.02.5±2.30.97
Alcohol, n (%)196 (45.0)217 (54.1)0.0081
Smoking, n (%)35 (8.0)71 (17.7)<0.0001
PDSS-2 total score15.4±9.39.2±6.0<0.0001
 PD-related sleep problems, n (%)153 (35.1)28 (7.0)<0.0001
ESS total score8.4±5.26.1±3.5<0.0001
 EDS, n (%)165 (37.8)62 (15.5)<0.0001
RBDSQ-J total score3.9±2.81.6±1.8<0.0001
 pRBD, n (%)153 (35.1)31 (7.7)<0.0001
  • ESS, Epworth Sleepiness Scale; RBDSQ-J, REM sleep behaviour screening questionnaire-Japanese version; EDS, excessive daytime sleepiness (ESS ≥10); PD, Parkinson’s disease; PD-SP, PD-related sleep problems (PDSS-2 ≥18); PDSS-2, PD sleep scale-2; pRBD, probable RBD (RBDSQ J ≥5).