Regular ArticleProfiling Neurosteroids in Cerebrospinal Fluids and Plasma by Gas Chromatography/Electron Capture Negative Chemical Ionization Mass Spectrometry
References (31)
The neuropsychopharmacological potential of neuroactive steroids
J. Psychiatr. Res.
(1997)- et al.
GABAA-dependent modulation of the Cl− ionophore by steroids in rat brain
Eur. J. Pharmacol.
(1987) - et al.
Anxiolytic Effect of 3α-hydroxy-5α[β]-pregnan-20-one: Endogenous metabolite of progesterone that are active at the GABAA receptor
Brain Res.
(1991) - et al.
Receptor binding and electrophysiological effect of dehydroepiandrosterone sulfate, an antagonist of the GABAa receptor
Neuroscience
(1991) - et al.
Isonizid-induced inhibition of GABAergic transmission enhances neurosteroid content in the rat brain
Neuropharmacology
(1996) - et al.
The endozepine triakontatetraneuropeptide diazepame-binding inhibitor[17-50] stimulates neurosteroid biosynthesis in the frog hypothalamus
Neuroscience
(1998) - et al.
Radioimmunoassay of 3α-hydroxy-5α-pregnan-20-one in rat and human plasma
Steroids
(1990) - et al.
Determination of cortisol in human plasma by gas chromatography/negative ion chemical ionization/mass spectrometry
Anal. Biochem.
(1994) - et al.
Simultaneous quantitation of endogenous levels of cortisone and cortisol in human nasal and bronchoalveolar lavage fluids and plasma via gas chromatography-negative ion chemical ionization mass spectrometry
Anal. Biochem.
(1994)
Measurement of plasma testosterone by gas chromatography–negative-ion mass spectrometry using pentafluoropropionic derivatives
J. Chromatogr. B Biomed. Appl.
Analysis of steroids from normal and tumor tissue by HPLC
Clin. Chim. Acta
Cortisol production rates measured by liquid chromatography/mass spectrometry
Steroids
Determination of steroids by liquid chromatography/mass spectrometry
J. Am. Soc. Mass Spectrom.
A reference method for the analysis of aldosterone in blood by high-performance liquid chromatography–atmospheric pressure chemical ionization–tandem mass spectrometry
Anal Biochem
Cited by (77)
Determination of neurosteroids in human cerebrospinal fluid in the 21st century: A review
2020, Journal of Steroid Biochemistry and Molecular BiologyCitation Excerpt :Due to the chemical structure of steroids, derivatization is predominantly performed to enhance stability and volatility, improve signal intensity, lower detection limits and produce characteristic fragmentation patterns supporting identification. Nearly equally used ionization procedures in the available studies were electron ionization (EI) [64,77] or chemical ionization (CI) [76,78,79]. Generally, well established and easy reproducible derivatisation procedures are available for steroid analysis.
Dissecting the syndrome of schizophrenia: Associations between symptomatology and hormone levels in women with schizophrenia
2019, Psychiatry ResearchCitation Excerpt :Although sex hormones can easily traverse the blood-brain-barrier due to their high lipid solubility, it should be acknowledged that peripheral levels of steroids may not reflect levels in the central nervous system (CNS), due to the regional variability in neural tissue (Heringa et al., 2015), and the intrinsic ability of the brain to synthesis local neurosteroids. However, positive correlations have been demonstrated in rat between plasma levels and brain levels of neurosteroids (Barbaccia et al., 2001), and in humans between plasma and cerebral spinal fluid (CSF) levels (Kim et al., 2000). Despite these limitations, this study is the first, to our knowledge, to characterise and cluster the conditional effects of pituitary and sex hormones on psychopathology scores in a sample of female patients with schizophrenia.
Collection and Analyses of Cerebrospinal Fluid for Pediatric Translational Research
2019, Pediatric Neurology
- 1
To whom correspondence should be addressed. Fax: (301) 594-0035. E-mail: [email protected].