Elsevier

NeuroImage

Volume 3, Issue 2, April 1996, Pages 97-103
NeuroImage

Regular Article
Visualizing Cortical Activation during Mental Calculation with Functional MRI

https://doi.org/10.1006/nimg.1996.0011Get rights and content

Abstract

Cortical activation during arithmetic calculation (silent subtraction by sevens) was compared to that observed during a control condition for which subjects were required to count forward by ones. Nine normal subjects underwent 1.5-T functional magnetic resonance imaging while performing these tasks. All subjects showed bilateral premotor, posterior parietal, and prefrontal cortex activation during serial calculation. There was a large degree of individual variation in activation outside of these areas. These results confirm the role of posterior parietal cortex in arithmetic calculation and implicate other regions, including prefrontal cortex.

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