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Mitochondrial encephalomyopathy (MELAS) with mental disorder

CT, MRI and SPECT findings

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Summary

A case of mitochondrial encephalomyopathy (MELAS) with mental disorder is reported. The SPECT study using123I-iodoamphetamine (IMP) and MRI study revealed abnormality in the left parieto-occipital areas without abnormality in the brain CT or brain scintigram. These findings suggest a localized dysfunction of the brain capillary endothelium in association with the cerebral involvement of mitochondrial encephalomyopathy.

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Suzuki, T., Koizumi, J., Shiraishi, H. et al. Mitochondrial encephalomyopathy (MELAS) with mental disorder. Neuroradiology 32, 74–76 (1990). https://doi.org/10.1007/BF00593949

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