Major depressive disorder in coronary artery disease☆
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2019, Handbook of Behavioral NeuroscienceCitation Excerpt :Changes in the cardiovascular system are prevalent in MDD, and there appears to be a bi-directional relationship between cardiovascular disorders and MDD. Thus, rates of depression in patients with cardiovascular disease range from 20% to 40% (Carney et al., 1987). Conversely, a recent meta-analysis including over 120,000 patients showed that depression increased the risk of cardiovascular incidents by 80%–90% (Nicholson, Kuper, & Hemingway, 2006).
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This work was supported in part by a grant from the National Research and Demonstration Center, by SCOR in Ischemic Heart Disease and by grant HL 17464 from the National Institutes of Health, Bethesda, Maryland, and by a grant from the American Heart Association, St. Louis Affiliate.
Copyright © 1987 Published by Elsevier Inc.