Iontophoretic studies of some trace amines in the mammalian CNS
References (21)
- et al.
Phenylethylamine: evidence for a direct postsynaptic dopamine-receptor stimulating action
Brain Research
(1977) - et al.
Trace amines and alternative neurotransmitters in the central nervous system
Biochem. Pharmacol.
(1978) - et al.
A reappraisal of the actions of noradrenaline and 5-hydroxytryptamine on cerebral cortical neurons
Comp. gen. Pharmacol.
(1972) - et al.
Iontophoretic study of the effects of norepinephrine and 2-phenylethylamine on single cortical neurons
Life Sci.
(1973) - et al.
Actions of microiontophoretically applied p-andm-tyramine on caudate neurons
Abstr. Europ. Soc. Neurochem.
(1976) Cerebral aryl alkyl aminergic mechanisms
Trace amines in the central nervous system
The tyramines: functionally significant amines or metabolic accidents?
Life Sci.
(1978)- et al.
Octopamine receptors on aplysia neurons mediate hyperpolarization by incressing membrane conductance
Nature (Lond.)
(1974) - et al.
Lack of specificity of motorneurone responses to microintophoretically applied phenolic amines
Acta physiol. scand.
(1976)
Cited by (26)
A Tyramine-Gated Chloride Channel Coordinates Distinct Motor Programs of a Caenorhabditis elegans Escape Response
2009, NeuronCitation Excerpt :Tyramine increases chloride conductance in the Drosophila Malpighian (renal) tubules (Blumenthal, 2005). Furthermore in rats, tyramine induces strong inhibitory effects on the firing rate of caudate and cortical neurons (Henwood et al., 1979) and can induce hyperpolarization in neurons of the subthalamic nucleus (Zhu et al., 2007) of the rat brain. The analysis of escape responses in flies, crayfish and goldfish have illuminated how neural networks translate sensory input into a motor output (Korn and Faber, 2005; Edwards et al., 2002; Allen et al., 2006).
The mysterious trace amines: Protean neuromodulators of synaptic transmission in mammalian brain
2006, Progress in NeurobiologyCitation Excerpt :In general, these complex interactions between TRP and serotonin may be important for TRP in controlling the balance between the excitatory and inhibitory effects of serotonin on cortical neurons (Jones, 1982e). In general, the iontophoretic ejection of p-TYR, m-TYR, p-OA and β-PEA elicits rapid hyperpolarizations at currents of administration comparable to, or slightly greater than, those necessary for hyperpolarizations elicited by dopamine and noradrenaline (Boakes et al., 1976; Bevan et al., 1978; Henwood et al., 1979; Jones and Boulton, 1980b). Whereas the responses to these trace amines have been described as weaker and more variable than those induced by dopamine and noradrenaline (Bevan et al., 1978; Jones and Boulton, 1980a), they are readily reversible, longer lasting, and in a few cases have been reported as occurring independently of any indirect presynaptic release of dopamine and noradrenaline or serotonin (Hoffer et al., 1971; Engberg et al., 1976; Jones, 1982b).
Effects of β-phenylethylamine on the hypothalamo-pituitary-adrenal axis in the male rat
2000, Pharmacology Biochemistry and BehaviorPhenylethylaminergic modulation of catecholaminergic neurotransmission
1991, Progress in Neuropsychopharmacology and Biological Psychiatryβ-phenylethylamine enhances single cortical neurone responses to noradrenaline in the rat
1988, Brain Research Bulletin
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Present address: Department of Anatomy, The University of Texas, Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78284, U.S.A.