Cerebral blood flow in schizophrenia
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A systematic review and meta-analysis of the effects of antipsychotic medications on regional cerebral blood flow (rCBF) in schizophrenia: Association with response to treatment
2014, Neuroscience and Biobehavioral ReviewsCitation Excerpt :One cross-sectional study included medication-naïve patients, and also reported no differences compared to treated patients. However, the sample size was so small (n = 3) that it may have lacked statistical power (Dousse et al., 1988). Instead, longitudinal studies of antipsychotic-naïve patients provide a more powerful design to investigate potential effects.
On the sensitivity of ASL MRI in detecting regional differences in cerebral blood flow
2010, Magnetic Resonance ImagingCitation Excerpt :ASL MRI, as a biomarker for baseline neural activity, has great potentials in clinical applications. However, questions remained as to whether ASL MRI can detect small CBF differences on the order of 10%, which is the typical range of CBF deficit occurring in many psychiatric and neurological disorders [31–34]. The present study provides a systematic investigation into the detection power of ASL and the optimal strategies for data analysis.
Regional cerebral blood flow in first break and chronic schizophrenic patients and normal controls
1995, Schizophrenia ResearchRegional differentiation of cortical activity in schizophrenia: a complementary approach to conventional analysis of regional cerebral blood flow
1995, Psychiatry Research: NeuroimagingRegional cerebral blood flow in schizophrenia: Repeated studies during a psychotic episode
1990, Psychiatry Research: Neuroimaging
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We thank Mr. Ait-Bachir, Mrs. Agnèes Barrier, and Christine Dronneau for their technical assistance in the measurement of cerebral blood flow. This research was supported by INSERM, CNRS, and the University Paris VII.