Elsevier

Surgical Neurology

Volume 23, Issue 6, June 1985, Pages 567-572
Surgical Neurology

Spinal cord compression in neuroblastoma

https://doi.org/10.1016/0090-3019(85)90004-7Get rights and content

Abstract

Twelve of 80 patients suffering from neuroblastoma who were treated during a 21-year period had intraspinal in-involvement. Mediastinal tumors have a greater tendency to extend to the spinal canal; however, distant spread of the tumor is rare in patients presenting with intraspinal extension. Patients with intraspinal extension also survive longer than those without. Other factors affecting survival are age, stage of disease, duration of neurological symptoms, degree of histologic differentiation, and mode of therapy. In the absence of osseous metastasis, total excision of the primary lesion and its intraspinal components is usually followed by a favorable outcome; residual neurological deficits among survivors, however, are relatively common.

References (26)

  • CJ Fagan et al.

    Dumbbell neuroblastoma or ganglioneuroma of the spinal canal

    AJR

    (1974)
  • J Fortner et al.

    Neuroblastoma: natural history and results of treating 133 cases

    Ann Surg

    (1968)
  • RE Gross et al.

    Neuroblastoma sympatheticum, a study and report of 217 cases

    Pediatrics

    (1959)
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