Tissue-type plasminogen activator in the chronic subdural hematoma
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2022, World NeurosurgeryCitation Excerpt :Vascular endothelial growth factor is also present in high levels causing a dysregulated neoangiogenic process and forming immature capillaries that can be easily disrupted or leak.4,5 Furthermore, it is also thought that increased levels of tissue plasminogen activator can be responsible for continuous fibrinolysis, precluding resolution of blood collection.10,14 The primary therapeutic mechanism of statins consists of inhibition of β-hydroxy β-methylglutaryl coenzyme A reductase leading to a lipid-lowering effect.11,15
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Copyright © 1988 Published by Elsevier Inc.