Original articleDoes chloroquine cause seizures? Presentation of three new cases and a review of the literature
References (10)
- et al.
Drug-induced neurological disorders
Adverse Drug Reaction and Acute Poisoning Review
(1988) Drug-induced convulsions
Lancet
(1972)- et al.
Convulsions associated with prophylactic antimalarial drugs: implications for people with epilepsy
British Medical Journal
(1988) - et al.
Malaria prophylaxis and epilepsy
British Medical Journal
(1988) - et al.
Verdacht auf anfallsfördernde wirkung von chloroquine (Resochin)
Nervenarzt
(1989)
Cited by (19)
Possible involvement of nitrergic and opioidergic systems in the modulatory effect of acute chloroquine treatment on pentylenetetrazol induced convulsions in mice
2016, Brain Research BulletinCitation Excerpt :Experimental studies reported NO as a neuromodulator with proconvulsive or anticonvulsive properties, depending on the convulsion models. In some case reports, possible stimulatory effects of chloroquine on seizures were discussed (Luijckx et al., 1992; Torrey, 1968). Moreover, in the chloroquine adverse effects profile, convulsions and also non convulsive status epilepticus have been mentioned (Fish and Espir, 1988; Mülhauser, 1995).
Attitudes and practices of families and health care personnel toward children with epilepsy in Kilifi, Kenya
2006, Epilepsy and BehaviorDoes mefloquine prophylaxis affect electroencephalographic patterns?
2002, American Journal of MedicineCitation Excerpt :We previously reported that mefloquine blood levels were not correlated with other serious adverse effects of mefloquine (22). An association between antimalarial medications and seizures has been noted with chloroquine as well (23–25). It may be a result of high concentrations of the drug in the cerebrospinal fluid, intracellular accumulation of the drug, genetic predisposition, or coadministration of other drugs (10).
Probing the Neuro-psychological Changes Observed with the Administration of COVID-19 Drugs
2023, Current Topics in Medicinal ChemistryUnderstanding and managing the impact of the COVID-19 pandemic and lockdown on patients with epilepsy
2022, Expert Review of Neurotherapeutics