Successful outcome of Scedosporium apiospermum disseminated infection treated with voriconazole in a patient receiving corticosteroid therapy

Clin Infect Dis. 2000 Dec;31(6):1499-501. doi: 10.1086/317496.

Abstract

A disseminated Scedosporium apiospermum infection was diagnosed in a woman with severe asthma and treated with corticosteroids. This fungi is resistant to fluconazole and amphotericin B. The infection was refractory to itraconazole, but responded successfully to voriconazole. A review of the literature is provided.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use*
  • Aged
  • Antifungal Agents / therapeutic use*
  • Asthma / complications
  • Asthma / drug therapy
  • Dermatomycoses / drug therapy
  • Dermatomycoses / microbiology
  • Female
  • Humans
  • Lung Diseases, Fungal / drug therapy
  • Lung Diseases, Fungal / microbiology
  • Mycetoma / complications
  • Mycetoma / drug therapy*
  • Mycetoma / microbiology
  • Pyrimidines / therapeutic use*
  • Scedosporium / drug effects
  • Scedosporium / isolation & purification*
  • Treatment Outcome
  • Triazoles / therapeutic use*
  • Voriconazole

Substances

  • Adrenal Cortex Hormones
  • Antifungal Agents
  • Pyrimidines
  • Triazoles
  • Voriconazole