Chemokines in the brain: neuroimmunology and beyond

Knut Biber; Mike W Zuurman; Inneke M Dijkstra; Hendrikus W G M Boddeke

doi:10.1016/s1471-4892(01)00122-9

Chemokines in the brain: neuroimmunology and beyond

Curr Opin Pharmacol. 2002 Feb;2(1):63-8. doi: 10.1016/s1471-4892(01)00122-9.

Authors

Knut Biber¹, Mike W Zuurman, Inneke M Dijkstra, Hendrikus W G M Boddeke

Affiliation

¹ Department of Medical Physiology, University of Groningen, A Deusinglaan 1, PO Box 196, 9700 AD Groningen, The Netherlands.

PMID: 11786310
DOI: 10.1016/s1471-4892(01)00122-9

Abstract

Chemokines in the brain have been recognised as essential elements in neurodegenerative diseases and related neuroinflammation. Recent studies suggest that in addition to the orchestration of chemotaxis of immune cells, chemokines are also involved in neurodevelopment and neurophysiological signalling.

Publication types

Review

MeSH terms

Animals
Brain / immunology*
Brain / metabolism
Brain / pathology
Chemokines / physiology*
Humans
Inflammation / immunology
Inflammation / pathology
Neuroimmunomodulation / physiology*
Receptors, Chemokine / physiology

Substances

Chemokines
Receptors, Chemokine