Type III glycogenosis with multicore structures

Muscle Nerve. 1979 Mar-Apr;2(2):124-32. doi: 10.1002/mus.880020207.

Abstract

A case of an infantile type III glycogenosis (Forbes disease), confirmed by morphologic and biochemical studies, had light-microscopic, histochemical, and electron-microscopic evidence of multicore structures and type 1 fiber predominance with hypotrophy. This association is discussed with relation to the unusual clinical findings. The authors conclude that two distinct disease entities--Forbes disease and multicore myopathy--may coexist.

Publication types

  • Case Reports

MeSH terms

  • Adenosine Triphosphatases / analysis
  • Child, Preschool
  • Female
  • Glycogen / analysis
  • Glycogen Storage Disease / pathology*
  • Glycogen Storage Disease Type III / metabolism
  • Glycogen Storage Disease Type III / pathology*
  • Histocytochemistry
  • Humans
  • Liver / analysis
  • Liver / pathology*
  • Liver / ultrastructure
  • Microscopy, Electron
  • Muscles / analysis
  • Muscles / pathology*
  • Muscles / ultrastructure
  • NADH Tetrazolium Reductase / analysis
  • Succinate Dehydrogenase / analysis

Substances

  • Glycogen
  • Succinate Dehydrogenase
  • NADH Tetrazolium Reductase
  • Adenosine Triphosphatases