Central and peripheral nervous system involvement in the L-tryptophan associated eosinophilia myalgia syndrome

L M Tolander; C R Bamford

doi:10.3109/00207459108986272

Central and peripheral nervous system involvement in the L-tryptophan associated eosinophilia myalgia syndrome

Int J Neurosci. 1991 Nov;61(1-2):69-75. doi: 10.3109/00207459108986272.

Authors

L M Tolander¹, C R Bamford

Affiliation

¹ Department of Neurology, University of Arizona, Tucson 85724.

PMID: 1809736
DOI: 10.3109/00207459108986272

Abstract

A case of L-tryptophan associated eosinophilia, myalgia, eosinophilic fasciitis, peripheral sensorimotor neuropathy, and multiple white matter lesions on MRI scan is reported. The various effects of eosinophilia on the nervous system are reviewed. The persistence of the neurological complications despite resolution of eosinophilia and steroid therapy is emphasized.

Publication types

Case Reports

MeSH terms

Aged
Brain / pathology
Central Nervous System / pathology*
Central Nervous System / physiopathology
Electromyography
Electrophysiology
Eosinophilia-Myalgia Syndrome / pathology*
Eosinophilia-Myalgia Syndrome / physiopathology
Female
Humans
Magnetic Resonance Imaging
Neural Conduction / physiology
Peripheral Nerves / pathology*
Peripheral Nerves / physiopathology
Tryptophan / adverse effects*

Substances

Tryptophan