Abstract
Thirteen patients with advanced multiple sclerosis and urge urinary incontinence were treated with desmopressin--a synthetic analogue of antidiuretic hormone--in a double-blind cross-over study. The micturition frequency decreased significantly (p less than 0.05). Less leakage was considered valuable for daily life. Peroral medication was favourable in these patients with muscular dysfunction. Side-effects were few.
Publication types
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Clinical Trial
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Comparative Study
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Randomized Controlled Trial
MeSH terms
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Administration, Oral
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Deamino Arginine Vasopressin / administration & dosage
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Deamino Arginine Vasopressin / therapeutic use*
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Double-Blind Method
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Female
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Humans
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Male
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Middle Aged
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Multiple Sclerosis / complications*
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Randomized Controlled Trials as Topic
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Urinary Bladder, Neurogenic / drug therapy*
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Urinary Bladder, Neurogenic / etiology
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Urinary Incontinence / drug therapy*
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Urinary Incontinence / etiology
Substances
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Deamino Arginine Vasopressin