Abstract
Interstitial pulmonary fibrosis is a serious complication of inflammatory muscle disease associated with significant morbidity and mortality. We describe 3 consecutive cases complicating dermatomyositis (1 case, anti-Jo-1 antibody negative) and polymyositis (2 cases, anti-Jo-1 antibody positive) in which cyclophosphamide was added to prednisone therapy with favorable outcomes.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Cyclophosphamide / therapeutic use*
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Dermatomyositis / complications*
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Dermatomyositis / drug therapy
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Drug Therapy, Combination
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Female
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Humans
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Male
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Myositis / complications*
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Myositis / drug therapy
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Prednisone / therapeutic use
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Pulmonary Fibrosis / drug therapy*
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Pulmonary Fibrosis / etiology
Substances
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Cyclophosphamide
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Prednisone