Abstract
A 72-year-old hypertensive man developed parkinsonism and was treated with Sinemet for 4 years but then died of a bronchial carcinoma. Necropsy revealed cerebrovascular disease and amyloid angiopathy. The substantia nigra and locus coeruleus were normal on light microscopy.
MeSH terms
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Aged
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Carbidopa / pharmacology*
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Drug Combinations / pharmacology
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Humans
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Levodopa / pharmacology*
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Locus Coeruleus / drug effects*
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Male
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Parkinson Disease / drug therapy*
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Substantia Nigra / drug effects*
Substances
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Drug Combinations
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carbidopa, levodopa drug combination
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Levodopa
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Carbidopa