Isolated motor control dysfunction related to progressive multifocal leukoencephalopathy during AIDS with normal MRI

B de Toffol; M Vidailhet; F Gray; J M Besnier; P Menage; M C Lescs; P Choutet; A Autret

doi:10.1212/wnl.44.12.2352

Isolated motor control dysfunction related to progressive multifocal leukoencephalopathy during AIDS with normal MRI

Neurology. 1994 Dec;44(12):2352-5. doi: 10.1212/wnl.44.12.2352.

Authors

B de Toffol¹, M Vidailhet, F Gray, J M Besnier, P Menage, M C Lescs, P Choutet, A Autret

Affiliation

¹ Clinique Neurologique, C.H.U. Bretonneau, Tours, France.

PMID: 7991125
DOI: 10.1212/wnl.44.12.2352

Abstract

We describe the case of a human immunodeficiency virus-infected 34-year-old man with progressive multifocal leukoencephalopathy (PML). His case displayed unusual features, including a bizarre movement disorder, predominant involvement of the subcortical U fibers on neuropathologic examination, and the absence of MRI abnormalities suggestive of PML. Anatomic-clinical correlations are discussed.

Publication types

Case Reports

MeSH terms

AIDS Dementia Complex / pathology*
AIDS Dementia Complex / physiopathology*
Acquired Immunodeficiency Syndrome / pathology
Acquired Immunodeficiency Syndrome / physiopathology*
Adult
Brain / pathology*
Brain / virology
Fatal Outcome
Humans
In Situ Hybridization
JC Virus / isolation & purification
Magnetic Resonance Imaging
Male
Movement Disorders / pathology
Movement Disorders / physiopathology*
Reference Values