Chronic inflammatory demyelinating polyneuropathy accompanied by hepatocellular carcinoma

Intern Med. 1997 Jan;36(1):53-5. doi: 10.2169/internalmedicine.36.53.

Abstract

We report a patient with chronic inflammatory demyelinating polyneuropathy (CIDP) accompanied by hepatocellular carcinoma (HCC). Due to the remarkable weakness in the lower limbs and loss of the position sense, he could not walk. On neurophysiological examination, he had impaired nerve conduction velocities. Biopsied nerve and muscle specimens demonstrated demyelination of nerve fibers and neurogenic degeneration of muscles. After steroid therapy he showed marked improvement in muscle strength and sensory function.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage
  • Carcinoma, Hepatocellular / complications*
  • Demyelinating Diseases / drug therapy
  • Demyelinating Diseases / etiology*
  • Demyelinating Diseases / physiopathology
  • Humans
  • Liver Neoplasms / complications*
  • Male
  • Methylprednisolone / administration & dosage
  • Middle Aged
  • Neural Conduction / drug effects
  • Paraneoplastic Syndromes / drug therapy
  • Paraneoplastic Syndromes / etiology*
  • Paraneoplastic Syndromes / physiopathology
  • Polyneuropathies / drug therapy
  • Polyneuropathies / etiology*
  • Polyneuropathies / physiopathology

Substances

  • Anti-Inflammatory Agents
  • Methylprednisolone