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Year Number of Results
2004 1
2005 1
2007 3
2008 1
2009 3
2010 2
2012 1
2013 2
2018 2
2021 1
2022 4
2023 2
2024 0

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20 results

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Page 1
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.
Guo W, Wang H, Kumar Tharkeshwar A, Couthouis J, Braems E, Masrori P, Van Schoor E, Fan Y, Ahuja K, Moisse M, Jacquemyn M, Furtado Madeiro da Costa R, Gajjar M, Balusu S, Tricot T, Fumagalli L, Hersmus N, Janky R, Impens F, Vanden Berghe P, Ho R, Thal DR, Vandenberghe R, Hegde ML, Chandran S, De Strooper B, Daelemans D, Van Damme P, Van Den Bosch L, Verfaillie C. Guo W, et al. Among authors: hersmus n. Alzheimers Dement. 2023 Apr;19(4):1245-1259. doi: 10.1002/alz.12760. Epub 2022 Aug 22. Alzheimers Dement. 2023. PMID: 35993441 Free PMC article.
HDAC3 Inhibition Stimulates Myelination in a CMT1A Mouse Model.
Prior R, Verschoren S, Vints K, Jaspers T, Rossaert E, Klingl YE, Silva A, Hersmus N, Van Damme P, Van Den Bosch L. Prior R, et al. Among authors: hersmus n. Mol Neurobiol. 2022 Jun;59(6):3414-3430. doi: 10.1007/s12035-022-02782-x. Epub 2022 Mar 23. Mol Neurobiol. 2022. PMID: 35320455 Free PMC article.
HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS.
Braems E, Bercier V, Van Schoor E, Heeren K, Beckers J, Fumagalli L, Dedeene L, Moisse M, Geudens I, Hersmus N, Mehta AR, Selvaraj BT, Chandran S, Ho R, Thal DR, Van Damme P, Swinnen B, Van Den Bosch L. Braems E, et al. Among authors: hersmus n. Acta Neuropathol. 2022 Sep;144(3):465-488. doi: 10.1007/s00401-022-02471-y. Epub 2022 Jul 27. Acta Neuropathol. 2022. PMID: 35895140 Free PMC article.
Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity.
Bogaert E, Boeynaems S, Kato M, Guo L, Caulfield TR, Steyaert J, Scheveneels W, Wilmans N, Haeck W, Hersmus N, Schymkowitz J, Rousseau F, Shorter J, Callaerts P, Robberecht W, Van Damme P, Van Den Bosch L. Bogaert E, et al. Among authors: hersmus n. Cell Rep. 2018 Jul 17;24(3):529-537.e4. doi: 10.1016/j.celrep.2018.06.070. Cell Rep. 2018. PMID: 30021151 Free PMC article.
Insights into the identification of a molecular signature for amyotrophic lateral sclerosis exploiting integrated microRNA profiling of iPSC-derived motor neurons and exosomes.
Rizzuti M, Melzi V, Gagliardi D, Resnati D, Meneri M, Dioni L, Masrori P, Hersmus N, Poesen K, Locatelli M, Biella F, Silipigni R, Bollati V, Bresolin N, Comi GP, Van Damme P, Nizzardo M, Corti S. Rizzuti M, et al. Among authors: hersmus n. Cell Mol Life Sci. 2022 Mar 14;79(3):189. doi: 10.1007/s00018-022-04217-1. Cell Mol Life Sci. 2022. PMID: 35286466 Free PMC article.
A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.
Swinnen B, Bento-Abreu A, Gendron TF, Boeynaems S, Bogaert E, Nuyts R, Timmers M, Scheveneels W, Hersmus N, Wang J, Mizielinska S, Isaacs AM, Petrucelli L, Lemmens R, Van Damme P, Van Den Bosch L, Robberecht W. Swinnen B, et al. Among authors: hersmus n. Acta Neuropathol. 2018 Mar;135(3):427-443. doi: 10.1007/s00401-017-1796-5. Epub 2018 Jan 4. Acta Neuropathol. 2018. PMID: 29302778
AAV9-mediated gene delivery of MCT1 to oligodendrocytes does not provide a therapeutic benefit in a mouse model of ALS.
Eykens C, Rossaert E, Duqué S, Rué L, Bento-Abreu A, Hersmus N, Lenaerts A, Kerstens A, Corthout N, Munck S, Van Damme P, Holt MG, von Jonquires G, Klugmann M, Van Den Bosch L, Robberecht W. Eykens C, et al. Among authors: hersmus n. Mol Ther Methods Clin Dev. 2021 Jan 20;20:508-519. doi: 10.1016/j.omtm.2021.01.006. eCollection 2021 Mar 12. Mol Ther Methods Clin Dev. 2021. PMID: 33614825 Free PMC article.
Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis.
Philips T, Bento-Abreu A, Nonneman A, Haeck W, Staats K, Geelen V, Hersmus N, Küsters B, Van Den Bosch L, Van Damme P, Richardson WD, Robberecht W. Philips T, et al. Among authors: hersmus n. Brain. 2013 Feb;136(Pt 2):471-82. doi: 10.1093/brain/aws339. Epub 2013 Jan 31. Brain. 2013. PMID: 23378219 Free PMC article.
TDP-43 M311V mutation in familial amyotrophic lateral sclerosis.
Lemmens R, Race V, Hersmus N, Matthijs G, Van Den Bosch L, Van Damme P, Dubois B, Boonen S, Goris A, Robberecht W. Lemmens R, et al. Among authors: hersmus n. J Neurol Neurosurg Psychiatry. 2009 Mar;80(3):354-5. doi: 10.1136/jnnp.2008.157677. J Neurol Neurosurg Psychiatry. 2009. PMID: 19228676 No abstract available.
20 results