User profiles for "author:Alberto Rábano"

Alberto Rábano

Neuropathology Department and Brain Bank, Fundación CIEN
Verified email at fundacioncien.es
Cited by 12315

Evidences for adult hippocampal neurogenesis in humans

EP Moreno-Jiménez, J Terreros-Roncal… - Journal of …, 2021 - Soc Neuroscience
The rodent hippocampus generates new neurons throughout life. This process, named adult
hippocampal neurogenesis (AHN), is a striking form of neural plasticity that occurs in the …

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer's disease

EP Moreno-Jiménez, M Flor-García… - Nature medicine, 2019 - nature.com
The hippocampus is one of the most affected areas in Alzheimer's disease (AD) 1. Moreover,
this structure hosts one of the most unique phenomena of the adult mammalian brain …

Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains

C Benito, E Núñez, RM Tolón, EJ Carrier… - Journal of …, 2003 - Soc Neuroscience
The endocannabinoid system is still poorly understood. Recently, the basic elements that
constitute it, ie, membrane receptors, endogenous ligands, and mechanisms for termination …

Methods to study adult hippocampal neurogenesis in humans and across the phylogeny

J Terreros‐Roncal, M Flor‐García… - …, 2023 - Wiley Online Library
The hippocampus hosts the continuous addition of new neurons throughout life—a
phenomenon named adult hippocampal neurogenesis (AHN). Here we revisit the …

Impact of neurodegenerative diseases on human adult hippocampal neurogenesis

J Terreros-Roncal, EP Moreno-Jiménez, M Flor-García… - Science, 2021 - science.org
Disrupted hippocampal performance underlies psychiatric comorbidities and cognitive
impairments in patients with neurodegenerative disorders. To understand the contribution of …

Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes

M Pajares, N Jiménez-Moreno, ÁJ García-Yagüe… - Autophagy, 2016 - Taylor & Francis
Autophagy is a highly coordinated process that is controlled at several levels including
transcriptional regulation. Here, we identify the transcription factor NFE2L2/NRF2 (nuclear …

[HTML][HTML] Oral microbiota, its equilibrium and implications in the pathophysiology of human diseases: a systematic review

B Giordano-Kelhoffer, C Lorca, J March Llanes… - Biomedicines, 2022 - mdpi.com
Imbalances of the oral microbiota and dysbiosis have traditionally been linked to the
occurrence of teeth and oral diseases. However, recent findings indicate that this microbiota …

α-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease

I Lastres-Becker, A Ulusoy… - Human molecular …, 2012 - academic.oup.com
Although α-synuclein (α-SYN) aggregation is a hallmark of sporadic and familial Parkinson's
disease (PD), it is not known how it contributes to early events of PD pathogenesis such as …

[HTML][HTML] Different brain regions are infected with fungi in Alzheimer's disease

D Pisa, R Alonso, A Rábano, I Rodal, L Carrasco - Scientific reports, 2015 - nature.com
The possibility that Alzheimer's disease (AD) has a microbial aetiology has been proposed
by several researchers. Here, we provide evidence that tissue from the central nervous …

[HTML][HTML] CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia

KL Williams, S Topp, S Yang, B Smith, JA Fifita… - Nature …, 2016 - nature.com
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are overlapping,
fatal neurodegenerative disorders in which the molecular and pathogenic basis remains …