Therapeutic activity is a mainstay of clinical neurorehabilitation, but is typically unstructured
and directed at compensation rather than restoration of central nervous system function …

Background and Purpose—Motor dysfunction after unilateral deafferentation in primates can
be overcome by restraining the unaffected limb. We asked whether a constraint-induced …

Lang CE, Edwards DF, Birkenmeier RL, Dromerick AW. Estimating minimal clinically
important differences of upper-extremity measures early after stroke. OBJECTIVE: To …

Restoration of human brain function after injury is a signal challenge for translational
neuroscience. Rodent stroke recovery studies identify an optimal or sensitive period for …

Although most current stroke intervention trials use disability scales to determine outcome,
little is known about the sensitivity to change of these scales. The use of a more sensitive …

Patients with mild stroke are assumed to achieve full recovery with little or no intervention.
However, recent studies suggest that such patients may experience persistent disability and …

Importance Clinical trials suggest that higher doses of task-oriented training are superior to
current clinical practice for patients with stroke with upper extremity motor deficits. Objective …

Stroke rehabilitation is evolving into a clinical field based on the neuroscience of recovery
and restoration. There has been substantial growth in the number and quality of clinical trials …

This study examined the reliability and validity of the Executive Function Performance Test
(EFPT). The EFPT assesses executive function deficits in the performance of real-world …

We have long known that language is lateralized to the left hemisphere (LH) in most
neurologically healthy adults. In contrast, findings on lateralization of function during …