Objective To determine the prevalence of hypermetabolism, relative to body composition, in
amyotrophic lateral sclerosis (ALS) and its relationship with clinical features of disease and …

This prospective cohort study,“Prospective Imaging Study of Ageing: Genes, Brain and
Behaviour”(PISA) seeks to characterise the phenotype and natural history of healthy adult …

The number produced on fluency tasks is widely used to measure voluntary response
generation. To further evaluate the relationship between generation, errors, and the area of …

Pathogenic variants in the gene encoding deleted in colorectal cancer (DCC) are the first
genetic cause of isolated agenesis of the corpus callosum (ACC). Here we present the …

Objective: Motor neurone disease [MND] encompasses broad cognitive impairments, which
are not fully captured by most screening tools. This study evaluated the specificity and …

Abstract Language disorders are increasingly recognised in Amyotrophic lateral sclerosis
(ALS), supporting the view of ALS as a multi-system disorder, impacting cognitive and motor …

Objective Inferring the emotional state or the true meaning of another person's utterance is a
key aspect of social cognition and critical for successful social interactions. In this study, we …

Aphasia assessment tools have primarily focused on classical aphasia type and severity,
with minimal incorporation of recent findings that suggest a significant role of executive …

Background: Apathy, characterized by a quantifiable reduction in motivation or goal-directed
behavior, is a multidimensional syndrome that has been observed across many …

Objective Hybrid teleneuropsychology has emerged as a useful assessment method to
manage physical distancing requirements during the COVID-19 pandemic. We describe the …