Traumatic brain injury (TBI) is still the leading cause of disability in young adults worldwide.
The major mechanisms–diffuse axonal injury, cerebral contusion, ischemic neurological …

Objective To assess the histologic accuracy of endoscopic biopsy samples of the pineal
region. Pineal region tumors usually present with acute hydrocephalus. Histologic diagnosis …

Distinct changes in glycogen synthase kinase-3 (GSK-3) signalling can regulate neuronal
morphogenesis including the determination and maintenance of axonal identity, and are …

Objectives External ventricular drain (EVD) insertion is a common neurosurgical procedure.
EVD-related infection (ERI) is a major complication that can lead to morbidity and mortality …

The expression and function of the 8 distinct catalytic isoforms of PI 3-kinase (PI3K) in the
nervous system are unknown. Whereas most PI3Ks have a broad tissue distribution, the …

The inactivation of glycogen synthase kinase-3β (GSK-3β) is proposed as the event
integrating protective pathways initiated by preconditioning and other interventions. The …

The use of therapeutic hypothermia in clinical medicine has become widely established in
the management of cardiac arrest and neonatal hypoxia, whereas the body of evidence in …

Interest in promoting regeneration of the injured nervous system has recently turned toward
the use of endogenous stem cells. Elucidating cues involved in driving these precursor cells …

Penetrating traumatic brain injury (PTBI) is one of the major cause of death and disability
worldwide. Previous studies with penetrating ballistic-like brain injury (PBBI), a PTBI rat …

Background. Chronic subdural haematoma (CSDH) is a common condition that increases in
incidence with rising age. Evacuation of a CSDH is one of the commonest neurosurgical …