The 2010 McDonald criteria for the diagnosis of multiple sclerosis are widely used in
research and clinical practice. Scientific advances in the past 7 years suggest that they might …

Neuroaxonal damage is the pathological substrate of permanent disability in various
neurological disorders. Reliable quantification and longitudinal follow-up of such damage …

Summary The 2015 Magnetic Resonance Imaging in Multiple Sclerosis and 2016
Consortium of Multiple Sclerosis Centres guidelines on the use of MRI in diagnosis and …

Cerebral small vessel disease (SVD) is a common accompaniment of ageing. Features seen
on neuroimaging include recent small subcortical infarcts, lacunes, white matter …

Background and Purpose—MRI is more sensitive than CT for detection of age-related white
matter changes (ARWMC). Most rating scales estimate the degree and distribution of …

We related the histopathologic changes associated with incidental white matter signal
hyperintensities on MRIs from 11 elderly patients (age range, 52 to 82 years) to a descriptive …

The type, frequency, and extent of MR signal abnormalities in Alzheimer's disease and
normal aging are a subject of controversy. With a 1.5-MR unit we studied 12 Alzheimer …

Background Under current guidelines, intravenous thrombolysis is used to treat acute stroke
only if it can be ascertained that the time since the onset of symptoms was less than 4.5 …

Background Glatiramer acetate, approved for the treatment of relapsing-remitting multiple
sclerosis, reduces relapses and disease activity and burden monitored by MRI. We …

Background: Multiple sclerosis (MS) is a complex disease with new drugs becoming
available in the past years. There is a need for a reference tool compiling current data to aid …