Accuracy of clinical diagnosis of Parkinson disease: a systematic review and meta-analysis
Objective: To evaluate the diagnostic accuracy of clinical diagnosis of Parkinson disease
(PD) reported in the last 25 years by a systematic review and meta-analysis. Methods: We …
(PD) reported in the last 25 years by a systematic review and meta-analysis. Methods: We …
[HTML][HTML] Diagnostic criteria for Parkinson's disease: from James Parkinson to the concept of prodromal disease
The diagnosis of Parkinson's disease (PD) is based on clinical features and differently to the
common opinion that detecting this condition is easy, seminal clinicopathological studies …
common opinion that detecting this condition is easy, seminal clinicopathological studies …
M itochondrial DNA and primary mitochondrial dysfunction in P arkinson's disease
In 1979, it was observed that parkinsonism could be induced by a toxin inhibiting
mitochondrial respiratory complex I. This initiated the long‐standing hypothesis that …
mitochondrial respiratory complex I. This initiated the long‐standing hypothesis that …
[PDF][PDF] TGR5-mediated bile acid sensing controls glucose homeostasis
TGR5 is a G protein-coupled receptor expressed in brown adipose tissue and muscle,
where its activation by bile acids triggers an increase in energy expenditure and attenuates …
where its activation by bile acids triggers an increase in energy expenditure and attenuates …
[PDF][PDF] The third gas: H2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis
S Fiorucci, E Antonelli, A Mencarelli, S Orlandi… - …, 2005 - Wiley Online Library
The regulation of sinusoidal resistance is dependent on the contraction of hepatic stellate
cells (HSC) around sinusoidal endothelial cell (SEC) through paracrine cross‐talk of …
cells (HSC) around sinusoidal endothelial cell (SEC) through paracrine cross‐talk of …
[HTML][HTML] TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading
TWH Pols, M Nomura, T Harach, GL Sasso… - Cell metabolism, 2011 - cell.com
The G protein-coupled receptor TGR5 has been identified as an important component of the
bile acid signaling network, and its activation has been linked to enhanced energy …
bile acid signaling network, and its activation has been linked to enhanced energy …
Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs
S Fiorucci, E Antonelli, E Distrutti, G Rizzo, A Mencarelli… - Gastroenterology, 2005 - Elsevier
Background & Aims: Hydrogen sulfide (H2S), an endogenous gaseous mediator that causes
vasodilation, is generated in mammalian tissues by cystathionine β-synthase (CBS) and …
vasodilation, is generated in mammalian tissues by cystathionine β-synthase (CBS) and …
The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis
S Fiorucci, E Antonelli, G Rizzo, B Renga, A Mencarelli… - Gastroenterology, 2004 - Elsevier
Background & Aims: The farnesoid X receptor (FXR) is an endogenous sensor for bile acids
and inhibits bile acid synthesis by inducing small heterodimer partner (SHP) gene …
and inhibits bile acid synthesis by inducing small heterodimer partner (SHP) gene …
Idebenone treatment in Leber's hereditary optic neuropathy
Sir, We have read with great interest the results presented by Klopstock et al.(2011)
concerning the RHODOS study on a clinical trial with idebenone in Leber's hereditary optic …
concerning the RHODOS study on a clinical trial with idebenone in Leber's hereditary optic …
[HTML][HTML] Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane: retention of caveolin-2 at the level of the golgi complex
I Parolini, M Sargiacomo, F Galbiati, G Rizzo… - Journal of Biological …, 1999 - ASBMB
Caveolins-1 and-2 are normally co-expressed, and they form a hetero-oligomeric complex in
many cell types. These caveolin hetero-oligomers are thought to represent the assembly …
many cell types. These caveolin hetero-oligomers are thought to represent the assembly …