Introduction Breast cancer remains a significant scientific, clinical and societal challenge.
This gap analysis has reviewed and critically assessed enduring issues and new challenges …

Background Little is known about the effect of sex on age-related changes in brain structure.
Methods Quantitative magnetic resonance imaging of the brain was performed in 330 …

Breast cancer is an increasing public health problem. Substantial advances have been
made in the treatment of breast cancer, but the introduction of methods to predict women at …

Objective To characterize the prevalence of amyloid deposition in a clinically unimpaired
elderly population, as assessed by Pittsburgh Compound B (PiB) positron emission …

Our understanding of the relationship between physical activity and health is constantly
evolving. Therefore, the British Association of Sport and Exercise Sciences convened a …

Context Ginkgo biloba is widely used for its potential effects on memory and cognition. To
date, adequately powered clinical trials testing the effect of G biloba on dementia incidence …

Objective: To test the hypothesis that quantitative variation in eating behaviour traits shows a
graded association with weight in children. Design: Cross-sectional design in a community …

Objective: We describe the sampling, initial evaluation, and final diagnostic classification of
subjects enrolled in a natural history study of Alzheimer's disease (AD). Design: Volunteer …

The amyloid cascade hypothesis suggests that the aggregation and deposition of amyloid-β
protein is an initiating event in Alzheimer's disease (AD). Using amyloid imaging technology …

Purpose: We evaluated the effect of weight loss on urinary incontinence (UI) in overweight
and obese women. Materials and Methods: A randomized, controlled clinical trial was …