Aminopyridines for the treatment of neurologic disorders
Purpose of review: To identify the different indications for the treatment of neurologic
disorders with the potassium channel blockers 4-aminopyridine (4-AP) and 3, 4 …
disorders with the potassium channel blockers 4-aminopyridine (4-AP) and 3, 4 …
Aldehyde dehydrogenase 1 positive glioblastoma cells show brain tumor stem cell capacity
M Rasper, A Schäfer, G Piontek, J Teufel… - Neuro …, 2010 - academic.oup.com
Glioblastoma (GBM) is the most aggressive primary brain tumor and is resistant to all
therapeutic regimens. Relapse occurs regularly and might be caused by a poorly …
therapeutic regimens. Relapse occurs regularly and might be caused by a poorly …
[HTML][HTML] Effects of acetyl-dl-leucine in patients with cerebellar ataxia: a case series
M Strupp, J Teufel, M Habs, R Feuerecker, C Muth… - Journal of …, 2013 - Springer
No existing medication has yet been shown to convincingly improve cerebellar ataxia.
Therefore, the identification of new drugs for its symptomatic treatment is desirable. The …
Therefore, the identification of new drugs for its symptomatic treatment is desirable. The …
A randomised double-blind, cross-over trial of 4-aminopyridine for downbeat nystagmus—effects on slowphase eye velocity, postural stability, locomotion and …
J Claassen, R Spiegel, R Kalla, M Faldon… - Journal of Neurology …, 2013 - jnnp.bmj.com
Objective The effects of 4-aminopyridine (4-AP) on downbeat nystagmus (DBN) were
analysed in terms of slow-phase velocity (SPV), stance, locomotion, visual acuity (VA) …
analysed in terms of slow-phase velocity (SPV), stance, locomotion, visual acuity (VA) …
Aldehyde dehydrogenase 1A1—a new mediator of resistance to temozolomide in glioblastoma
A Schäfer, J Teufel, F Ringel, M Bettstetter… - Neuro …, 2012 - academic.oup.com
Implementation of chemotherapy with the drug temozolomide increased the overall survival
of patients with glioblastoma multiforme (GBM; WHO grade IV), in particular when the O6 …
of patients with glioblastoma multiforme (GBM; WHO grade IV), in particular when the O6 …
Update on the pharmacotherapy of cerebellar ataxia and nystagmus
K Feil, T Bremova, C Muth, R Schniepp, J Teufel… - The Cerebellum, 2016 - Springer
Pharmacological treatment of cerebellar ataxias and cerebellar nystagmus still remains
difficult. The efficacy of most of the agents recommended in the past for symptomatic or even …
difficult. The efficacy of most of the agents recommended in the past for symptomatic or even …
Ocular VEMPs indicate repositioning of otoconia to the utricle after successful liberatory maneuvers in benign paroxysmal positioning vertigo
T Bremova, O Bayer, Y Agrawal, O Kremmyda… - Acta oto …, 2013 - Taylor & Francis
Conclusions: This study showed a transient increase of ocular vestibular evoked myogenic
potential (oVEMP) amplitudes in the affected ear after successful liberatory maneuvers and …
potential (oVEMP) amplitudes in the affected ear after successful liberatory maneuvers and …
Fampridine and acetazolamide in EA2 and related familial EA: a prospective randomized placebo-controlled trial
C Muth, J Teufel, L Schöls, M Synofzik… - Neurology: Clinical …, 2021 - AAN Enterprises
Objective To determine the efficacy and safety of the treatment with prolonged-release 4-
aminopyridine (fampridine) and acetazolamide for patients with episodic ataxia type 2 (EA2) …
aminopyridine (fampridine) and acetazolamide for patients with episodic ataxia type 2 (EA2) …
Effect of chlorzoxazone in patients with downbeat nystagmus: a pilot trial
K Feil, J Claaßen, S Bardins, J Teufel, S Krafczyk… - Neurology, 2013 - AAN Enterprises
Objective: Downbeat nystagmus (DBN) is the most frequent form of acquired persisting
fixation nystagmus with different symptoms such as unsteadiness of gait, postural instability …
fixation nystagmus with different symptoms such as unsteadiness of gait, postural instability …
[HTML][HTML] Update on the pharmacotherapy of cerebellar and central vestibular disorders
An overview of the current pharmacotherapy of central vestibular syndromes and the most
common forms of central nystagmus as well as cerebellar disorders is given. 4 …
common forms of central nystagmus as well as cerebellar disorders is given. 4 …