Clinical aspects and biological bases of drug-resistant epilepsies

G Regesta, P Tanganelli - Epilepsy research, 1999 - Elsevier
The definition of drug-resistant epilepsy (DRE) is elusive and still controversial owing to
some unresolved questions such as: how many drugs should be tried before a patient is …

Mass spectrometry‐based proteomics: The road to lung cancer biomarker discovery

…, E Marcelli, F Pentimalli, P Tanganelli… - Mass spectrometry …, 2013 - Wiley Online Library
Lung cancer is the leading cause of cancer death in men and women in Western nations,
and is among the deadliest cancers with a 5‐year survival rate of 15%. The high mortality …

Advanced glycation end products activate endothelium through signal-transduction receptor RAGE: a mechanism for amplification of inflammatory responses

…, G Lazzerini, M Massaro, T Simoncini, P Tanganelli… - Circulation, 2002 - Am Heart Assoc
Background—The products of nonenzymatic glycation and oxidation of proteins, the
advanced glycation end products (AGEs), form under diverse circumstances such as aging …

Usefulness of atrial deformation analysis to predict left atrial fibrosis and endocardial thickness in patients undergoing mitral valve operations for severe mitral …

…, M Chiavarelli, M Massetti, P Tanganelli… - The American journal of …, 2013 - Elsevier
In patients with severe mitral regurgitation (MR) referred for cardiac surgery, left atrial (LA)
remodeling and enlargement are accompanied by mechanical stress, mediated cellular …

Smooth muscle cells of the media in the dilatative pathology of ascending thoracic aorta: morphology, immunoreactivity for osteopontin, matrix metalloproteinases, and …

V Lesauskaite, P Tanganelli, C Sassi, E Neri, F Diciolla… - Human pathology, 2001 - Elsevier
The etiopathogenesis of thoracic aortic aneurysms is currently an issue of debate. The
present study investigated ultrastructural, morphometric, and immunohistochemical aspects …

Neoangiogenesis, T-lymphocyte infiltration, and heat shock protein-60 are biological hallmarks of an immunomediated inflammatory process in end-stage calcified …

…, M Glauber, A Biagini, P Tanganelli - Journal of the American …, 2004 - jacc.org
Objectives: We investigated the main biomolecular features in the evolution of aortic
stenosis, focusing on advanced lesions. Background:“Degenerative” aortic valve stenosis …

Early neonatal brain injury in histologic chorioamnionitis

…, M Stumpo, E Picciolini, T Todros, P Tanganelli… - The Journal of …, 2001 - Elsevier
The relation between clinical or histologic chorioamnionitis and early neonatal adverse
neurologic outcome was investigated (n= 483). Histologic, but not clinical, evidence of …

The number of pregnancies is a risk factor for Alzheimer's disease

…, N Dagnino, C Mariani, P Tanganelli - European journal of …, 2006 - Wiley Online Library
Epidemiological data show a higher prevalence of late‐onset Alzheimer's disease (AD) in
women. The estrogenic deficiency in the post‐menopausal period is suspected to be the …

Incidence rate of primary cardiac tumors: a 14-year population study

…, M Chiavarelli, M Glauber, P Tanganelli… - Journal of …, 2016 - journals.lww.com
Aims Incidence of primary cardiac tumors (PCTs) is not known. Literature data derive from
autoptic studies or echocardiographic registries. An incidence of 1 of 1000 autoptic and 1.5 …

RV longitudinal deformation correlates with myocardial fibrosis in patients with end-stage heart failure

…, C Tsioulpas, S Bernazzali, P Tanganelli… - JACC: Cardiovascular …, 2015 - jacc.org
Objectives: This study was performed to determine the accuracy of right ventricular (RV)
longitudinal strain (LS) in predicting myocardial fibrosis in patients with severe heart failure …