The retina is an easily accessible part of the CNS with a well-defined cytological
architecture. It allows for detailed study of the regulation of neurogenesis, determinants of …

ACCUMULATION of the prion protein PrPSc, a pathological and protease-resistant isoform
of the normal host protein PrPc, is a feature of prion disease such as scrapie1, 2. It is still …

LIMB muscles develop from cells that migrate from the somites1, 2. The signal that induces
migration of myogenic precursor cells to the limb emanates from the mesenchyme of the …

The maintenance of bone marrow stromal stem cells (BMSSCs) is tightly controlled by the
local microenvironment and by autocrine regulatory factors secreted by BMSSCs. To identify …

Non-motor symptoms are now commonly recognized in Parkinson's disease (PD) and can
include dysautonomia. Impairment of cardiovascular autonomic function can occur at any …

E-selectin (ELAM-1) and P-selectin (GMP-140, PADGEM, CD62) have both been described
as human endothelial cell adhesion molecules for neutrophils and monocytes. Cell surface …

Abstract The methyltransferase, Enhancer of Zeste homology 2 (EZH2), trimethylates histone
3 lysine 27 (H3K27me3) on chromatin and this repressive mark is removed by lysine …

E-SELECTIN is an inducible cell-adhesion molecule on endothelial cells, which mediates
the binding of neutrophils and functions as a Ca2+-dependent lectin1–3. We have recently …

Macrophages are thought to represent a first line of defense in anti‐tumor immunity. Despite
infiltration by microglial cells, however, malignant gliomas are still highly aggressive tumors …

The TWIST family of basic helix‐loop‐helix transcription factors, Twist‐1 and Dermo‐1 are
known mediators of mesodermal tissue development and contribute to correct patterning of …