Interleukin 6 plays a key role in the development of antigen-induced arthritis

S Ohshima, Y Saeki, T Mima, M Sasai… - Proceedings of the …, 1998 - National Acad Sciences
To investigate the direct role of interleukin (IL) 6 in the development of rheumatoid arthritis,
IL-6-deficient (IL-6−/−) mice were backcrossed for eight generations into C57BL/6 mice, a …

Volume analyzer SYNAPSE VINCENT for liver analysis

S Ohshima - Journal of Hepato‐Biliary‐Pancreatic Sciences, 2014 - Wiley Online Library
In recent years, there has been an active movement to ensure the greater safety of actual
surgeries, by simulating it preoperatively with the use of three‐dimensional image …

[PDF][PDF] An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies

…, M Kohyama, K Tomii, K Ohmura, S Ohshima… - Cell, 2021 - cell.com
Antibodies against the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein
prevent SARS-CoV-2 infection. However, the effects of antibodies against other spike …

Polymer composites of carbon nanotubes aligned by a magnetic field

T Kimura, H Ago, M Tobita, S Ohshima… - Advanced …, 2002 - Wiley Online Library
Anisotropic carbon nanotube–polyester composites have been realized by polymerization of
the nanotube–monomer dispersion in a constant magnetic field (see Figure for method) …

J apan as the front‐runner of super‐aged societies: Perspectives from medicine and medical care in J apan

…, M Yokode, H Rakugi, S Ohshima - Geriatrics & …, 2015 - Wiley Online Library
Background The demographic structure of a country changes dramatically with increasing
trends toward general population aging and declining birth rates. In J apan, the percentage …

Long-term outcome of laparoscopic radical nephrectomy for pathologic T1 renal cell carcinoma

…, O Kamihira, Y Yoshikawa, Y Yoshino, S Ohshima - Urology, 2003 - Elsevier
OBJECTIVES: To evaluate the oncologic adequacy of laparoscopic radical nephrectomy in
patients with pathologic Stage T1 renal cell carcinoma, we analyzed the long-term results in …

Renal L-type fatty acid–binding protein in acute ischemic injury

…, M Goto, N Shinozaki, S Ohshima… - Journal of the …, 2007 - journals.lww.com
Fatty acid–binding proteins (FABPs) bind unsaturated fatty acids and lipid peroxidation
products during tissue injury from hypoxia. We evaluated the potential role of L-type FABP (L …

Mineralocorticoid receptor antagonism ameliorates left ventricular diastolic dysfunction and myocardial fibrosis in mildly symptomatic patients with idiopathic dilated …

…, H Asano, T Amano, S Ichihara, T Kato, S Ohshima… - Circulation, 2005 - Am Heart Assoc
Background—Mineralocorticoid receptor antagonism reduces mortality associated with
heart failure by mechanisms that remain unclear. The effects of the mineralocorticoid …

Galectin 3 and its binding protein in rheumatoid arthritis

S Ohshima, S Kuchen, CA Seemayer… - Arthritis & …, 2003 - Wiley Online Library
Objective To characterize the expression pattern and role of galectin 3 and galectin 3
binding protein (G3BP) in rheumatoid arthritis (RA), in comparison with galectin 1, and to …

Selectivity of water-soluble proteins in single-walled carbon nanotube dispersions

K Matsuura, T Saito, T Okazaki, S Ohshima… - Chemical physics …, 2006 - Elsevier
Proteins were screened by preparing dispersions of SWNTs to investigate the driving force
of the interaction between single-walled carbon nanotubes (SWNTs) of mean diameter 1nm …