The quality of life in Parkinson's disease

AM Kuopio, RJ Marttila, H Helenius… - … : official journal of the …, 2000 - Wiley Online Library
The objective of this study was to examine the quality of life in patients with Parkinson's
disease (PD) in a community‐based sample (n= 228 patients) using a Medical Outcomes …

Dementia in Parkinson's disease is related to neuronal loss in the medial substantia nigra

JO Rinne, JR Mlic, L Paljärvi… - Annals of Neurology …, 1989 - Wiley Online Library
Regional neuronal loss in the substantia nigra was studied in relation to extrapyramidal
symptoms and dementia in 12 patients with idiopathic Parkinson's disease (PD) and in 18 …

Survival and cause of death in Alzheimer's disease and multi‐infarct dementia

PK Mölsä, RJ Marttila, UK Rinne - Acta Neurologica …, 1986 - Wiley Online Library
Survival and causes of death of 218 patients with Alzheimer's disease (AD) and of 115
patients with multi‐infarct dementia (MID) were examined. The patients were originally found …

Entacapone enhances the response to levodopa in parkinsonian patients with motor fluctuations

UK Rinne, JP Larsen, A Siden, J Worm-Petersen… - Neurology, 1998 - AAN Enterprises
Objective: To study the effect and safety of entacapone as an adjunct to levodopa treatment
in patients with PD with wearing-off motor fluctuations. Background: Entacapone is a …

Early treatment of Parkinson's disease with cabergoline delays the onset of motor complications: results of a double-blind levodopa controlled trial

UK Rinne, F Bracco, C Chouza, E Dupont, O Gershanik… - Drugs, 1998 - Springer
This multicentre randomised double-blind 3-to 5-year trial was designed to assess whether
initial therapy with cabergoline alone or in combination with levodopa prevents or delays the …

Correlation between neuromorphometry in the substantia nigra and clinical features in Parkinson's disease using disector counts

SY Ma, M Röyttä, JO Rinne, Y Collan… - Journal of the neurological …, 1997 - Elsevier
Previous studies based on single sections have suggested a significant correlation between
pigmented neuronal loss in the substantia nigra (SN) and clinical features in Parkinson's …

Oxygen toxicity protecting enzymes in Parkinson's disease: increase of superoxide dismutase-like activity in the substantia nigra and basal nucleus

RJ Marttila, H Lorentz, UK Rinne - Journal of the neurological sciences, 1988 - Elsevier
Oxygen-derived toxicity has been suggested as being involved in the pathogenesis of
Parkinson's disease. Superoxide dismutase, catalase, glutathione peroxidase, and …

Long‐term survival and predictors of mortality in Alzheimer's disease and multi‐infarct dementia

PK Mölsä, RJ Marttila, UK Rinne - Acta neurologica …, 1995 - Wiley Online Library
Long‐term survival was examined for 218 patients with Alzheimer's disease (AD) and 115
patients with multi‐infarct dementia (MID). The 14‐year survival rate for AD was 2.4% versus …

Progression and survival in Parkinson's disease

RJ Marttila, UK Rinne, RJ Marttila - Acta Neurologica …, 1991 - Wiley Online Library
Parkinson's disease is a progressive disorder and no permanent cure has ever been
documented. The clinical onset, which usually occurs at an age of 55–65 years, is probably …

Essential tremor in a Finnish population

I Rautakorpi, J Takala, RJ Marttila… - Acta Neurologica …, 1982 - Wiley Online Library
A two‐phase epidemiological study of essential tremor was carried out by investigating a
rural population aged over 40 years in 2 municipalities in southwestern Finland. In the first …