Treatments in depression

F Duval, BD Lebowitz, JP Macher - Dialogues in clinical …, 2006 - Taylor & Francis
Major depression is believed to be a multifactorial disorder involving predisposing
temperament and personality traits, exposure to traumatic and stressful life events, and …

First-night effect in normal subjects and psychiatric inpatients

M Toussaint, R Luthringer, N Schaltenbrand, G Carelli… - Sleep, 1995 - academic.oup.com
The goal of the present study was to evaluate the first-night effect in psychiatric inpatients
using large subject samples (n> 30) in order to obtain a good statistical evaluation. Thirty …

Facial expressiveness in patients with schizophrenia compared to depressed patients and nonpatient comparison subjects

F Trémeau, D Malaspina, F Duval… - American Journal of …, 2005 - Am Psychiatric Assoc
OBJECTIVE: Blunted affect is a major symptom in schizophrenia, and affective deficits
clinically encompass deficits in expressiveness. Emotion research and ethological studies …

Central effects of acamprosate: part 1. Acamprosate blocks the glutamate increase in the nucleus accumbens microdialysate in ethanol withdrawn rats

A Dahchour, P De Witte, N Bolo, JF Nédélec… - Psychiatry Research …, 1998 - Elsevier
One of the known behavioral actions of acamprosate is to decrease hypermotility during
alcohol withdrawal. However, the mechanism of this effect remains unclear. In this study, the …

Brain pharmacokinetics and tissue distribution in vivo of fluvoxamine and fluoxetine by fluorine magnetic resonance spectroscopy

NR Bolo, Y Hodé, JF Nédélec, E Lainé… - …, 2000 - Elsevier
This investigation of fluvoxamine and fluoxetine-norfluoxetine distributions in vivo at steady-
state and of quantitative kinetics in brain and plasma after drug therapy interruption was …

Efficacy and safety of hydroxyzine in the treatment of generalized anxiety disorder: a 3-month double-blind study

PM Llorca, C Spadone, O Sol, A Danniau… - Journal of Clinical …, 2002 - psychiatrist.com
Background: The prevalence of generalized anxiety disorder (GAD) represents an important
public health issue. Hydroxyzine, an antagonist of histamine receptors, showed both efficacy …

Sleep stage scoring using the neural network model: comparison between visual and automatic analysis in normal subjects and patients

N Schaltenbrand, R Lengelle, M Toussaint… - Sleep, 1996 - academic.oup.com
In this paper, we compare and analyze the results from automatic analysis and visual
scoring of nocturnal sleep recordings. The validation is based on a sleep recording set of 60 …

A quantitative evaluation of the relationships between growth hormone secretion and delta wave electroencephalographic activity during normal sleep and after …

C Gronfier, R Luthringer, M Follenius, N Schaltenbrand… - Sleep, 1996 - academic.oup.com
The existence of a relationship between growth hormone (GH) release and slow-wave sleep
(SWS), often studied in the past using conventional scoring of sleep stages, remains …

Cortisol hypersecretion in unipolar major depression with melancholic and psychotic features: dopaminergic, noradrenergic and thyroid correlates

F Duval, MC Mokrani, JA Monreal-Ortiz, S Fattah… - …, 2006 - Elsevier
Evidence supports that hyperactivity of the hypothalamic–pituitary–adrenal axis has a pivotal
role in the psychobiology of severe depression. The present study aimed at assessing …

Sleep microstructure around sleep onset differentiates major depressive insomnia from primary insomnia

L Staner, F Cornette, D Maurice… - Journal of sleep …, 2003 - Wiley Online Library
In the present study we investigate whether alterations of sleep propensity or of wake
propensity are implicated in sleep initiation disturbances encountered in major depressive …