Aspects of the pathogenesis of cerebral schistosomiasis have been elucidated. Arterial embolization alone, by either worms or eggs, does not appear to be likely as a major cause of the disease. When large numbers of eggs enter the brain, sensitization may play a role in the occurrence of neurological signs. These studies support but do not prove the theory that worms in the cerebral veins lay eggs that then cause the disease.
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