You are here

Article Text

Article menu
Download PDFPDF
Articles
Uptake and release of 14C-5-hydroxytryptamine by platelets in affective illness
  1. David M. Shaw,
  2. David A. MacSweeney,
  3. Norman Woolcock,
  4. A. B. Bevan-Jones
  1. Medical Research Council Neuropsychiatry Unit, West Park Hospital, Epsom, London
  2. Carshalton Surrey, St. Bartholomew's Hospital, London
  3. The Department of Psychological Medicine, St. Bartholomew's Hospital, London

    Abstract

    In the search for paradigms of postulated abnormalities in indolamine function in the brain in affective disorders, 5-HT uptake and release was estimated in platelets from patients suffering from severe depressive illness. Neither of these measures was altered by the illness and the most likely explanation for the negative findings was that in this setting platelets are not a suitable model.

    https://doi.org/10.1136/jnnp.34.3.224

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.